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Spring 2023:

see this clip to get you thinking about course content:

https://www.youtube.com/watch?v=WVvKnq5XT-g

Lecture: Biological Sciences, Rm. 116, T and TH
LABS: See Canvas for course ( Lab web pages from 2011 have some resources you might find of use)

Text book: It is listed in canvas. I strongly enourge you to have a text book to read sections related to the topics covered in lecture and lab.

Why comparative neurophysiology is of interest [ PDF ]

FREE NEUROPHYSIOLOGY TEXT BOOK ON LINE (use for a review of basic concepts)
http://nba.uth.tmc.edu/neuroscience/m/s1/index.htm

Free background information on neuron morphology, conducting electrical, ionic bases of resting & action potential, and Synapse structure

Dr. Melody Danley
mlda227@uky.edu

Office: 153 C, NEW ACADEMIC SCI BUILDING

Office Hours: email for time

Teaching assistants for the course:

Shea Carr, sesi229@g.uky.edu ..............Maria Venegas, Maria.Venegas@uky.edu...................Rhoda Inimgba, tin224@uky.edu

Course schedule (see below) (go to)

BIO350: Lecture Schedule for Bio 350, Spring 2023, All Sections

THIS SCHEDULE MAY CHANGE AS WE GO ALONG. So updates will be posted in Canvas.

Lecture, Day, Topic Reading

Outline of lecture schedule and do list here:

Week 1

Week 2

Week 3 .

................PDF 1-Evol. Med PDF or MS WORD

................PDF 2- Ice Fish PDF or MS WORD

Look at oxidative stress paper (PDF)

To the issue about CHOLESTEROL and fluidity of biological membranes within normal temperatures. There maybe differences in the teaching on this point in Cell Biology and Animal Physiology so keep in mind which system, animal or bacteria, and the normal operating temperatures for the organisms.

In relation to Bio350 ANIMAL physiology and NOT bacterial cells the point is that cholesterol decreases fluidity in biological membranes of mammals.

Lets see the text by Lodish et al., (4th edition, 2000) Molecular Cell Biology

Page 165:

"Membrane cholesterol is another major determinate of bilayer fluidity....... The net effect of cholesterol on membrane fluidity varies, depending on the lipid composition. ...... At the high concentrations found in eukaryotic plasma membranes, cholesterol tends to make the membranes less fluid at growth temperatures near 37C."

Neat Information:

Muscle cramp and K + : http://www.ncbi.nlm.nih.gov/pubmed/23182013 " CONCLUSIONS: The effect of banana ingestion on EAMCs is unknown; however, these data suggested bananas are unlikely to relieve EAMCs by increasing extracellular [K(+)] or [glucose](p). The increases in [K(+)](p) were marginal and within normal clinical values. The changes in [K(+)](p), plasma K(+) content, and [glucose](p) do not occur quickly enough to treat acute EAMCs, especially if they develop near the end of competition."

..............................http://www.ncbi.nlm.nih.gov/pubmed/22157068..... Horses and hyperK diets http://www.ncbi.nlm.nih.gov/pubmed/10213428

Evolutionary Physiology 1994 (PDF)

.............PDF 1-Evol. Med PDF or MS WORD

................PDF 2- Ice Fish PDF or MS WORD

About Myelin (PDF1) & (PDF2)

About folic acid (pdf)

Male Brain (pdf)

Drug MDMA (ectasy) (PDF)

neg pH (pdf)

Imprint genes (pdf)

Music & Brain (pdf)

Kiss & Run (pdf)

Neat PDF on nerve gas agents (PDF)

The leech model and glia cells (PDF)

Muscle Growth (PDF)

Skeletal muscle fatigue (PDF)

Heart. MEA in rats PDF

OVERHEADS used in class: