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BIOLOGY 350- ANIMAL PHYSIOLOGY

GO TO lab www pages HERE

The lecture part of CLASS only meets on Tuesday & Thursdays

(See correction from class overhead on ATP count-PDF)

NOTE : about MONDAY LAB (PDF)

Room 116 Biology
Watch these videos Windows Media VERSION Part 1 & part 2

Dr. Thomas Kaufman's seminar. These are big files. You have to download to your computer, then open to watch. Think about what significance do fruit flies serve for breakthroughs in understanding diseases that inflict humans?

OLD EXAMS (used in a summer course; MS Word 2003 format)

2006 summer Test 1, Test 2, Test 3, Test 4

2009 summer Test1, Test 2, Test 3, Test 4

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Fall 2010:

Biology Building

 

.............................................

Lecture: Biological Sciences, Rm. 116
LABS: (lab www page) Rm 202

Sec 001 : Monday 9:00 - 11:50 AM
Sec 002 :
Monday 12:00 - 2:50 PM
Sec 003 :
Wednesday 8:00-10:50 AM
Sec 004 :
Wednesday 11:00 -1:50 PM
Sec 005 :
Wednesday 2:00 - 4:50 PM
Sec 006 :
Friday 9:00 - 11:50 AM

Text book: It is listed in Kennedy's Book store under "Bio 350"

Title: Eckert Animal Physiology: Mechanisms and Adaptations, Fifth Edition, by David Randall, Warren Burggren, and Kathleen French.
http://www.whfreeman.com/newcatalog.aspx?isbn=0716738635

BIOLOGY 350- ANIMAL PHYSIOLOGY
Instructor: Teaching assistants for the course:
Dr. Robin L. Cooper
RLCOOP1@email.uky.edu
Office: Morgan building-226
Tel: 257-5950
Office Hours: email for time
WWW Home page (go to)

Sec 002 & 006

Tim Bradshaw
Biology Department
ttbrad2@email.uky.edu

Office: Room
tel

Teaching assistants for the course:

Sec 001 & 004

Ms. WenHui Wu
wuwenhui2@gmail.com
Office: Room 226
Tel: 257-5950
Office Hours: email for appt.

Sec 003 & 005

Cliff Harpole
ceharpole@gmail.com
Biology Department
Office: Room
tel:


Down load PDF files: Course rules (see below) Chapter questions to focus on (go to)
Jump to on this page:

Course schedule (see below) (go to)

Download PPT files (go to)

COURSE OUTLINE

Biology 350

BIO350: Lecture Schedule for Bio 350, FALL 2010 (T & TH 8:00 AM- 9:15 AM)

Lecture, Day, Date, Topic Reading, Lecturer (note --download podcast to your own computer then open)

1. TH 8/26 Introduction to course and physiology Chapt 1&2, 3 (podcast 082610 ....23 MB file)
2. T 8/31 Molecules, Energy and Biosynthesis Chapt 3 (podcast 083110, also PDF of ATP count)
3. TH 9/2 Membranes, Channels and Transport/ Physical basis of neuronal function Chapt. 4 & 5 (podcast 090210)
.......M 9/6 Holiday---Labor day. NO LAB ON MONDAY. All other labs will meet this week.
4. T 9/7 Physical basis of neuronal function Chapt. 5 (podcast 090710 Also to help relax you for the exam try this )
5. TH 9/9 Communication along and between neurons Chapt. 6 (we will probably only get through Chapter 5, but concepts from LAB will be on the exam such as length constant that is also in Chapter 6). (podcast 090910)

............................T ... 9/14 Exam 1........ (NOTE : about MONDAY LAB (PDF))
6. TH 9/16 Communication along and between neurons Chapt. 6 (podcast 091610)
7. T 9/21 Communication along and between neurons Chapt. 6 (podcast 092110, also so you can chill out a little play)
8. TH 9/23 Sensory Mechanisms Chapt. 7
( I am behind in lecture, Podcast wrap up Ch 6 092310, not on podcast is going over exam that we covered in class)
9. T 9/28 Sensory Mechanisms Chapt. 7 (podcast here ch 6 and start ch 7 092810)

(HERE is a cool paper on many of the proteins associated with vessicles in the nerve terminal- just check out the figures... so neat PDF version & no I am not testing you on this paper, except for the concepts we taked about in class)


10. TH 9/30 Sensory Mechanisms/ Organization of Nervous System Chapt. 7-8 (podcast 093010)
11. T 10/5 Muscle Chapt. 10 (podcast 100510)

12. TH 10/7 Muscle & Behavior Ch 10-11 (podcast 100710) ( I know, stress for lab report and paper is building. So here are two stress reduction events for you Stress test reduction, Stress lab report reduction)
13. T 10/12 Muscle & Behavior Ch 10-11 & review (podcast 101210)
................................TH 10/14 Exam 2 Ch 6-11 (w/o 9)
14. T10/19 Hormones, mechanisms of action Chapt. 9 (podcast 10192010; Also I know that school is adding stress -so here is more stress reduction -- play here)

15. TH 10/21 Hypothalamus-Pituitary Chapt. 9 (podcast 10212010 )
16. T 10/26 Thyroid, parathyroid, adrenal and pancreas Chapt. 9 (podcast 10262010)
17. TH 10/28 Cardiovascular Chapt. 12 (Podcast 10282010) neat heart development PPT & endocrine PPT related to human health. Pacemaker control update PDF

18. T 11/2 Cardiovascular Chapt. 12 (podcast 11022010)
19. TH 11/4 Cardiovascular Chapt. 12 (Podcast 11042010)
20. T 11/9 Cardiovascular Chapt. 12. Might be able to start Respriation here (chapter 13) or have a review. (with guest lecture by Dr. Mark Bonnell) (podcast 11092010) (also to help hipe you up for studying play)
.......................................TH 11/11 Exam 3
21. T 11/16 Respiration Chapt. 13 (podcast 11162010)
22. TH 11/18 Respiration Chapt. 13 (podcast 11182010)
23. T 11/23 Ionic and Osmotic Balance Chapt. 14 (podcast 11232010) (Also to deal with relatives over the holiday play)
..... TH 11/25 Holiday - Thanksgiving (Monday lab can make up the lab you missed on 9/6 from Holiday)
24. T 11/30 Ionic and Osmotic Balance Chapt. 14 (podcast 11302010-- this one will help you fall asleep)
25. TH 12/1 Digestion Chapt. 15, overview of Chapters 16 & 17 (podcast 1202010)
26. T 12/6 Digestion Chapt. 15, overview of Chapters 16 & 17 (podcast 12072010 )

27. TH 12/9 CATCH UP DAY (review day, podcast 12092010 ) com'on get with it....play

............................Thurs., 12/16/10; FINAL EXAM @ 8:00 AM Room 116 Biology

FALL 2010

In this course you will gain knowledge of and an appreciation for the amazing diversity of strategies animals have developed for being able to survive, reproduce, and THRIVE in every ecosystem on this planet. Penguins survive beautifully in Antarctica, but humans can only survive there using extraordinary measures we would die within minutes if left naked on the shelf. You will learn WHY penguins survive and we cannot; why some people are diabetic, and how insulin can control this disease. You will also find out what happens to your body during exams (sure stress, but what IS stress and why is it sometimes very useful, other times, deadly?). You'll be able to amaze your friends, your parents, your employers with your grasp and knowledge of the intricacies of animal physiology, why starfish 'explode' if placed in freshwater, what commonalties we share with whales, and much more. So, get 'psyched' and get ready to work! There is a lot to learn, but if you keep at it consistently, you'll keep your stress levels down and enjoy the course.

One way of defining life is by the living organism's ability to maintain an internal environment which is different from the external environment. Furthermore, living organisms maintain a relatively constant internal environment in spite of the changing external environment. This phenomena was first clearly described by the great French physiologist Claude Bernard. The object of this course will be for you to learn how various organ systems function to bring about a relatively stable internal environment. To fully understand how organs accomplish homeostasis you must be able to apply the basic principles of mathematics, chemistry, physics and biochemistry.

Your understanding of homeostasis and the underlying principles will be tested four times during the semester. Each examination may consist of multiple choice, true/false, short answer and/or essay questions. Each of the first 3 examinations will have a possible 90 points. The fourth exam will be a mix final exam and material covered since the last exam worth 140 points. The fourth exam will have a substantial part of comprehensive material. There will only be one make-up exam if one of the other exams is missed. The make-up will take place immediately after the fourth exam during the second hour of the two hours allotted during the final exam period. The makeup will be a comprehensive exam covering the material during the entire course. Exams may include take home essays or essays assigned in class prior to exam dates to take home and complete prior to each exam. The grades on these essays may factor into the lecture exam grade. The essays are to be emailed and/or printed out as the assignment will state. These essays will be posted on blackboard and/or the class www page. It will be the students responsibility to check the blackboard and/or www page for assignments and the due dates.

There is a 3 hour lab period with this course. The object of this lab is for you to ask questions about any material that you did not understand in either the lectures. Questions are listed for each chapter which you should understand. These can be discussed during the lab time. You will receive two points for coming to lab. Lab is the time to ask! Your teaching assistants are at these labs to help you; however, if you do not prepare yourself by reading and trying to understand the course material they will not be able to help. Teaching assistants need feedback at these sessions; they are not there to lecture and add new material. They are there to help you understand the material, therefore you must know before you arrive what you do not understand. Attendance will be taken at each lab and you will be given 2 points each time you attend. Short quizzes may also be given at the beginning of class and count in the grading of the recitation part of the course. The fraction of the lab grade for the course will equal 50 points (the total points from assignments and attendance will be normalized so that 50 total points will be obtained for a perfect record).

Lab reports: 10 points each (2 lab write ups = 20 points)

Lab performance: 10 points 1st half of course for lab performace; 10 points 2nd half of course for lab performance. This is graded based on you getting data into your facilitator for the section and participating in the laboratory excercises. (= 20 points).

GRADES
There will be a total of approximately 500 points in this course: 90 pts for Exam 1, 90 points for Exam 2, 90 points for exam 3 and 140 points for Exam 4 as well as 50 points for attending each lab along with handing in homework. Two lab write ups =20 and lab performace = 20.The final grades will be assigned based on calculated percentages.

Total = 500 points
Grade Calculated Percentage Points
A 100-90.0
B 89.9-80.0
C 79.9-70.0
D 69.9-60.0
E 59.9 or lower
*This grading scale is based on expected performance in past sections, however, we reserve the right to make any necessary changes to the grading scale based on the final grade distributions.

UNIVERSITY POLICY ON EXCUSED AND UNEXCUSED ABSENCES
The following are acceptable reasons for excused absences:
1. serious illness of student (doctor's note required)
2. illness or death of family member (doctor's note required)
3. University related trips (such as to a football game for a team member or band member, official note required)
4. Major religious holidays. Students MUST notify instructor IN WRITING of all semester holidays to assure being excused.

ABSENCE FROM LAB, MISSED HOMEWORK ASSIGNMENTS
If you miss a lab, or fail to hand in your homework at the beginning of class each week, you will lose the points associated with these. If you want credit for these omissions, you must contact your TA within three calendar days of the omission and present your TA with a doctor's note within 3 calendar days of the omission. If you missed the lab or did not hand in your data or take the quiz on time due to reasons other than illness, assignment of credit is at the discretion of the TA. You will find that it is in your best interest to hand in data assignments and take the quiz, even if late, although you may not receive credit for them.

MAKE UP EXAMS
If you miss an EXAM #1, 2 or 3, you will have to make up the missed exam in the hour immediately following the 1st hour of Exam #4. These make-ups will be comprehensive over the entire textbook.

If you miss two exams you will be encourage to take an incomplete in the course.

In all cases, you must present a doctor's note, or other (as outlined above) to the instructors within 3 calendar days of missing any exam.

There is no make up exam for EXAM #4 (Final). If you miss the final, you will not be able to take an incomplete in the course without discussing with us the reasons for missing the exam, and then filling out and signing an incomplete form with the department. If we feel an incomplete is warranted, we will determine the conditions necessary to satisfy the incomplete at that time.

REGRADING EXAMS
We are happy to fix any errors or irregularities in grades. If you feel that there was an error in grading your exam, you must submit your request in writing, detailing which questions you feel are in error and why your answer(s) should receive additional credit. For instance, if there is information in the text book that supports your answer, quote the information from the book and provide the page and paragraph number. All requests must be submitted within 1 week of posting of the answer key in order for the scores to be changed.

CHEATING AND PLAGIARISM
Cheating and plagiarism are academic offenses that are not tolerated at the University of Kentucky. The minimum for either of these offenses is a failure in the course. Suspension and dismissal may result from repeated or more serious offenses.

DEAD WEEK

As previously noted, "Dead Week" refers to the final week of classes prior to final examinations. In 2009, the University Senate modified the Dead Week Policy as follows:

5.2.4.6 Dead Week [US: 4/13/09]

1. The last week of instruction of a regular semester is termed "Dead Week.” In the rest of these Rules, this term also refers to the last three days of instruction of a summer session and a summer term.
2. In cases of "Take Home" final examinations, students shall not be required to return the completed examination before the regularly scheduled examination period for that course.
3. No written examinations, including final examinations, may be scheduled during the Dead Week.
4. No quizzes may be given during Dead Week.
5. No project/lab practicals/paper/presentation deadlines or oral/listening examinations may be scheduled to fall during the Dead Week unless it was scheduled in the syllabus AND the course has no final examination (or assignment that acts as a final examination) scheduled during finals week. A course with a lab component may schedule the lab practical of the course during Dead Week if the lab portion does not also require a Final Examination during finals week.
6. Make-up exams and quizzes are allowed during Dead Week; these are exempt from the restrictions stated in C, D and E.
7. Class participation and attendance grades are permitted during Dead Week.
8. The current wording of this rule does not prohibit continuing into Dead Week regularly assigned graded homework that was announced in the class syllabus. [RC: 9/09]


Suggested questions at the end of each chapter

Ch. 1: Chapter 1: 1, 2

........PDF of text handed out in class

................PDF 1-Evol. Med PDF or MS WORD

................PDF 2- Ice Fish PDF or MS WORD

Look at oxidative stress paper (PDF)

Ch. 2: NA

Ch. 3: 8, 12, 13, 18, 19, 20, 21, 30

Lactate, not pyruvate, is neuronal aerobic glycolysis end product: an in vitro electrophysiological study. {PDF}

 

Ch. 4: 1, 10,11, 13, 15, 19

Ch. 5: 3, 4, 6. 9, 16, 19

Chapter 6: 2, 3 . Also fun sensory activities in lab as well as going over the exam.

Chapter 6: 7, 8, 12, 14, 18

Chapter 7:1, 2, 3, 7, 10, 14

Mean quantal content HW Handed out. See these if you loose the one in recitation: PDF , MS word or Gif file

Chapter 8: 3, 6, 9

Week of Oct 5 discuss [PDF4] & [PDF5]

Chapter 10: 1, 3, 6, 12, 19, 22

READ OVER : PDF 1, PDF 2

here is a general link (go to)

Chapter 11: 2, 13

You should be able to answer these questions (you might see them again) !

Reading: in chapter 9

Questions for recitation

1. Discuss the differences between autocine, paracrine, neurocrine and endocrine secretion.

2. What are pheromones?

3. Explain how catecholamines can have so many different actions.

4. Discuss examples that illustrate the intimate functional association of the nervous and endocrine systems.

5. How can a single second messenger, (e.g. cAMP or IP3) induced by binding of different hormones, mediate different cellular responses in different tissues?

6. Explain how a small number of hormone molecules can elicit cell responses involving millions of times as many molecules?

 

 

EXTRA Note:

To the issue about CHOLESTEROL and fluidity of biological membranes within normal temperatures. There maybe differences in the teaching on this point in Cell Biology and Animal Physiology so keep in mind which system, animal or bacteria, and the normal operating temperatures for the organisms.

In relation to Bio350 ANIMAL physiology and NOT bacterial cells the point is that cholesterol decreases fluidity in biological membranes of mammals.

Lets see the text by Lodish et al., (4th edition, 2000) Molecular Cell Biology

Page 165:

"Membrane cholesterol is another major determinate of bilayer fluidity....... The net effect of cholesterol on membrane fluidity varies, depending on the lipid composition. ...... At the high concentrations found in eukaryotic plasma membranes, cholesterol tends to make the membranes less fluid at growth temperatures near 37C."


DOWNLOAD Powerpoint files (as PDF files or ppt files)

Chapter 1-3 {ppt} {PDF}

Chapter 4 {ppt} {PDF}

Chapter 5 {ppt} {PDF}

Chapter 6 {ppt-a} {PDF-a}, {ppt-b} {PDF-b}

Chapter 7 {ppt-a} {PDF-a}, {ppt-b} {PDF-b}

Chapter 8 {ppt} {PDF}

Chapter 10 {ppt-a} {PDF-a}, {ppt-b} {PDF-b}

Chapter 11 (ppt) {PDF}

 

chapter 9 {ppt-a; ppt--b} {PDF-a; PDF-b}

chapter 12 {ppt-a; ppt-b} {PDF-a; PDF-b}

chapter 13 {ppt-a; ppt-b} {PDF-a; PDF-b}

chapter 14 {ppt-a; ppt-b} {PDF-a; PDF-b}

chapter 15 {ppt-a; ppt-b} {PDF-a; PDF-b}

chapter 16 {ppt} {PDF}

chapter 17 {ppt} {PDF}

 

 

Neat Information:

About Myelin (PDF1) & (PDF2)

About folic acid (pdf)

Male Brain (pdf)

Drug MDMA (ectasy) (PDF)

neg pH (pdf)

Imprint genes (pdf)

Music & Brain (pdf)

Kiss & Run (pdf)

Neat PDF on nerve gas agents (PDF)

The leech model and glia cells (PDF)

 

 

STUDENT ACTIVITIES IN BIOLOGY

1. SPUR- Society for Promotion of Undergraduate Research.

It is a great new club for anyone in research, or who is interested in doing research.By the way, for those of you that were interested in getting a lab position, the first step is to fill out an application, the link below will take you directly to it. The application may seem long/unneccesary, but it is not a
selective process. http://www.uky.edu/EUREKA/SPUR/home.html

2. TRI- BETA

UK Beta Beta Beta Biology Honors Society

http://web.as.uky.edu/Biology/TriBeta/default.htm

 

OVERHEADS used in class:

 

 

 

In order of Last name "A" to "Z" or very close. (Last name as used on scantron- some people used their 1st name)

Code #

Test #1

 

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