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SPRING 2018 BIOLOGY 350 ANIMAL PHYSIOLOGY

Check often Canvas and web page for updates

GO TO LAB BIO350 web page

The lecture part of CLASS for sections 1-4 meets on Tue and Thursday

Room 116 Biology

Lecture 9:30 -10:45 AM Tue & Thur

(sections 1-4)


OLD EXAMS (used in a summer course; MS Word 2003 format)

2006 summer Test 1, Test 2, Test 3, Test 4

2009 summer Test1, Test 2, Test 3, Test 4

On Canvas will be a master test bank for years of old exam questions

Back to teaching page

Spring 2018:

Biology Building

 

see this clip to get you thinking about course content:

https://www.youtube.com/watch?v=WVvKnq5XT-g

Instructor: But did you resubmit lab reports to earn back points?
Student: No, but I wanted to.

Instructor: Did you come by office hours to ask for help?
Student: No, but I was going to.

Instructor: Did you attend every lecture?
Student: I attended the important ones. Doesn't that count?

 

Lecture: Biological Sciences, Rm. 116
LABS: See Canvas for course ( Lab web pages from 2011 have some resources you might find of use)

The Bio 350 teaching lab is located in the new Academic Science Building
Labs for sections 1-4:
Section 001: Academic Science Building, room 104, 9 to 12 Monday
Section 002: Academic Science Building, room 104, 12-3 Monday
Section 003: Academic Science Building, room 104, 3-6 Monday
Section 004: Academic Science Building, room 104, 9-12 Wed

Text book: It is listed in Book store under "Bio 350"
Neither book is required but you might want one as a reference.

Animal Physiology: From Genes to Organisms, 2nd Edition. Lauralee Sherwood | Hillar Klandorf | Paul Yancey. ISBN-13: 978-0840068651 or ISBN-10: 0840068654
or
Eckert Animal Physiology: Mechanisms and Adaptations, Fifth Edition, by David Randall, Warren Burggren, and Kathleen French. ISBN-13: 978-0716738633 or ISBN-10: 0716738635

Why comparative neurophysiology is of interest [ pdf ]

FREE NEUROPHYSIOLOGY TEXT BOOK ON LINE (use for a review of basic concepts)
http://nba.uth.tmc.edu/neuroscience/m/s1/index.htm

Free background information on neuron morphology, conducting electrical, ionic bases of resting & action potential, and Synapse structure

 


BIOLOGY 350- ANIMAL PHYSIOLOGY
Instructors:
Dr. Robin L. Cooper
RLCOOP1@email.uky.edu
Office: Morgan building-226
Tel: 257-5950
Office Hours: email for time
WWW Home page (go to)

Dr. Melody Danley
mlda227@uky.edu

Office: 153 C, NEW ACADEMIC SCI BUILDING

Office Hours: email for time

Teaching assistants & helpers for the course:

 

 

 

 

 

 

 

Jason Collett

jason.collett@uky.edu

 


Nadera Dabbain

Nida222@g.uky.edu

Kristen LaRue

kristen.larue@uky.edu

Victoria Thompson

tori.thompson@uky.edu

 

Jeffrey Chalfant

jeffrey.chalfant@uky.edu

Oluwabukola Omotola bukola.omotola@uky.edu


Down load PDF files: Course outline PDF, MS word  
Jump to on this page:

Course schedule (see below) (go to)

Download PPT files (go to)

COURSE OUTLINE

Biology 350

BIO350: Lecture Schedule for Bio 350, Spring 2018 Sections 1-4

Lecture, Day, Topic Reading

1 1/11 How one learns. Homeostasis, Krogh principle Introduction to course and physiology. (Why comparative physiology-PDF) (podcast, ECHO360, ms word file of looking up stuff)The last part of ECHO 360 was cut off. All should be on podcast. See, we can't realy on techology all the time.

Can't focus while studying.... turn off Facebook, texting and listen to this and read book.

Stress relaxation here and here .

2 1/16 Molecules, Energy and Biosynthesis Movie (NO SCHOOL DAY, PPT)
about COPD and O2 therapy (checkout this blog) and here is an Article (PDF)

3 1/18 Membranes, Channels and Transport/ Physical basis of neuronal function (podcast, ECHO360, see Tuesday's PPT)

4 1/23 Physical basis of neuronal function (podcast, ECHO360, PPT, ppt, ppt)

5 1/25 Physical basis of neuronal function (podcast, ECHO360, PPT see 3 sets of Tuesday's above)

6 1/30 Communication along and between neurons (podcast, ECHO360, ECHO lost screen capture so just audio but all ppt files shown are provided ) PPT-see 3 sets of Tuesday's above)


Chill out a bit with this here

7 2/1 Communication along and between neurons (podcast, ECHO360, ECHO lost screen capture so just audio but all ppt files shown are provided ) PPT--see 3 sets of Tuesday's above)

8 2/6 Communication along and between neurons (podcast, ECHO360, PPT-lecture 4 ppt & lecture 5 Start) lecture quiz !!!!!!!!!!!!!!!!!. QUIZ-KEY

9 2/8 Sensory Mechanisms. lecture quiz !!!!!!!!!!!!!!!!!!. (podcast, ECHO360, PPT-lecture 5) Quiz#2 Key here

You can do it.... think of this mouse (here)

10 2/13 Sensory Mechanisms (podcast, ECHO360, PPT)

EXAM DATES THIS EXAM WILL TAKE PLACE IN THE LAB. You have 2 hours.
(SECTIONS 1-3 in your scheduled lab time on FEB 12)
(SECTION 4 in your scheduled lab time on FEB 14)

COPIES of EXAMS PDFs

Section 1, podcast, ECHO360,

Section 2 , podcast, ECHO360,

Section 3 ,podcast, ECHO360,

Section 4 , podcast,

11 2/15 Sensory Mechanisms/ Organization of Nervous System (podcast, ECHO360, PPT-same as above) (lecture assignment PDF, MS Word)


The lab is will meet this week for sections 1-4 (sec 1-3 on Monday 2/19 and sec 4 on 2/21)
Going over exam scores and grading and maybe a lab demo.

12 2/20 Sensory Mechanisms/ Organization of Nervous System (podcast, ECHO360, PPT-#5).....Muscle (Muscle man Youtube Muscle man EMG music )

13 2/22 Muscle & Behavior (podcast, ECHO360, PPT-muscle)

14 2/27 Muscle & Behavior (podcast, ECHO360, PPT-muscle)

15 3/1 Catch up lectures. (podcast, ECHO360, PPT-muscle and ppt behavior)

In case you need to chillout and relax from stress go here

16 3/6 Behavior (podcast, ECHO360, PPT) Maybe in class quiz.

17 3/8 Endocrine ...Hypothalamus-Pituitary (podcast, ECHO360, PPT) ((lecture assignment DUE-Midnight..... PDF, MS Word)

3/12-3/15 No class, Spring break

18 3/20 Thyroid, parathyroid, adrenal and pancreas (podcast, ECHO360, PPT)

19 3/22 Cont. Endocrine (podcast, ECHO360, PPT- GRP update, PPT-1 and PPT-2)

Links used : https://mymonthlycycles.com/menstrual_cycle.jsp

https://en.wikipedia.org/wiki/Development_of_the_reproductive_system

https://courses.washington.edu/conj/bess/differentiation/differentiation.htm


20 3/27 Cardiovascular (podcast, ECHO360, PPT) QUIZ day
https://en.wikipedia.org/wiki/Einthoven%27s_triangle
http://courses.kcumb.edu/physio/ecg%20primer/ecgaxis.htm

21 3/29 Cardiovascular / Respiration (podcast, ECHO360, PPT )
To relax this weekend you need to hear this music maybe some more as well here
April 2 and April 4. LAB SECTIONS 1-4 WILL MEET THIS WEEK IN THE LAB FOR LAB DEMOS & EXAM REVIEW.

 

Echo for sec4 is the best quality so I just went with that one for the main overview to wrap up circulation for

all sections below. Podcast is from your own section.

Section 1: Echo lecture, echo review, podcast lecture (battery died), podcast review

Section 2: Echo lecture, echo review, podcast lecture, podcast review

Section 3: Echo lecture, echo review, podcast lecture , podcast review

Section 4: Echo lecture, echo review, podcast lecture , podcast review

22 4/3 Cardiovascular (podcast, ECHO360, PPT-TODAY'S material)

23 4/5 EXAM DAY IN LECTURE CLASS
A very cool YouTube clip sent by your last year classmate: It is 4 minutes long and definitely a good watch. https://www.youtube.com/watch?v=YDspP4BhlTw

Exam copies Version 2A....... Version 2B.....They are PDFs

24 4/10 Respiration (podcast, ECHO360, PPT)

25 4/12 Respiration/ Ionic and Osmotic Balance (podcast, ECHO360, PPT)


http://www.ekgusa.com/ceol/abgmap/bgmodul/cebgquiz/bgmapqc.htm
Ion Normal blood concentration range (mmol.L?1)
Sodium 135-145
Calcium 2.1-2.8
Potassium ~3.5-5.0
Chloride 95-105
pH 7.35-7.45
pCO2 35-45
HCO3- 22 to 26 mEq/liter ( some other sources 21-28 mEq/L)

26 4/17 Ionic and Osmotic Balance (podcast, ECHO360, PPT, PPT) QUIZ DAY-6th

27 4/19 Digestion / Heat and adaptations (podcast-part1 podcast-part2, ECHO360-1 and echo360-2, PPT, ppt-gi ) NO CLASS, but ECHO RECORDING WILL BE MADE FOR YOU DRAWING OF JGA TO GO WITH ECHO&PODCASTs PDF here

( gut brain connections) (current article on poop) (also drugs & the GUT)

28 4/24 Digestion / Heat and adaptations / Catch up (podcast, ECHO360, PPT-gi, ppt-wrap up) QUIZ DAY-7th

29 4/26 Heat and adaptations / Catch up & Exam review (podcast, ECHO360, PPT) QUIZ DAY-8th KEY FOR QUIZ 8

REVIEW....... Audio

Chill out a bit with this here  & have a good break here

A litte more chill'n here

.....5/1.......8:00 AM ....FINAL EXAM. Cumulative with emphasis on last 3rd section of class

http://www.uky.edu/registrar/content/spring-final-exam-schedule


BIO 350 Lab Schedule: See your Canvas page.

The outline presented above is a tentative plan for the semester. Specific topics and assignments are subject to change.

Principal Learning Objectives:
(Same learning objectives from http://courses.cit.cornell.edu/biog1440/)
1. To gain understanding of the principles of how animals work at the molecular, cellular, and systems levels. This understanding will come not by memorizing a large body of facts, but by developing mental models of the various physiological processes (e.g. transport processes, cell-cell signaling, metabolism, thermoregulation, circulation, respiration…) that underlie life.
2. To gain skill in thinking like a physiologist. This requires both asking and answering questions about physiology, and so involves observing phenomena, generating hypotheses about the underlying mechanisms, and devising tests of your hypotheses.
3. To appreciate the physiological similarities and differences between the physiologies of humans and other organisms, and so to understand how the study of physiology is thoroughly relevant to your own life and to the world around you.

Additional Lab Guidelines
An essential component of learning in physiology requires the use of live animals. It is impossible to demonstrate the full extent of possible responses through textbooks readings or lectures. As emerging professionals, it is expected that all students will demonstrate respect and maturity when working with these animals. If any disrespect or intentional cruelty is inflicted upon the animals, it may be reason to be expelled from the course with an "I" (incomplete), "W" (withdrawal), or automatic "E" (failing grade) depending the timing and degree of the offense.
No horse play, cutting up, playing around, etc. is allowed in the laboratory. There are many students coming and going in the lab throughout the day and materials are sometimes shuffled around. Squirting someone with a solution in a syringe or a bottle can be dangerous. You might "know" it is water but another person does not. A 3M KCl solution can easily be mistaken for water, and can be very harmful if squirted by accident in someone's eye.

Every student will have to have completed the on line safety test and bring to the lab on the 1st day of your section meeting time. It is an easy test and you can take it multiple times until you get a 100 %. Either save and email your TA, or print it out and bring it to the first lab of the semester. The TA will check you off for having completed the exercise. The website for the safety test is:

http://ehs.uky.edu/authenticate.php

Animal care:
Even though you will be using primarily invertebrate animals in these laboratories no torture of the animals is allowed. If any torturing occurs to the animals it is reason to be expelled from the course with an "I" (incomplete) or possible a "W" (withdrawal) depending the timing within the semester.
No horse play, cutting up, playing ball etc.. allowed in the laboratory period. Squirting someone with a solution in a syringe or a water bottle can be dangerous. You might know it is water but another person does not. 3M KCl can be very harmful if squirted by accident in someone's eye.
We will use a fixative in the lab. The fix solution is a Bouin's solution (Prepared with saturated picric acid, formaldehyde and acetic acid; Sigma-Aldrich Co.). Some people are very allergic to the vapors of formaldehyde. If you know you are allergic please inform the instructor (Dr. Cooper) as soon as possible so we can make alternative plans. The fix solution is to remain in the vented hood.


 


Suggested readings

................PDF 1-Evol. Med PDF or MS WORD

................PDF 2- Ice Fish PDF or MS WORD

Look at oxidative stress paper (PDF)

 

 

 

 

 

EXTRA Note:

To the issue about CHOLESTEROL and fluidity of biological membranes within normal temperatures. There maybe differences in the teaching on this point in Cell Biology and Animal Physiology so keep in mind which system, animal or bacteria, and the normal operating temperatures for the organisms.

In relation to Bio350 ANIMAL physiology and NOT bacterial cells the point is that cholesterol decreases fluidity in biological membranes of mammals.

Lets see the text by Lodish et al., (4th edition, 2000) Molecular Cell Biology

Page 165:

"Membrane cholesterol is another major determinate of bilayer fluidity....... The net effect of cholesterol on membrane fluidity varies, depending on the lipid composition. ...... At the high concentrations found in eukaryotic plasma membranes, cholesterol tends to make the membranes less fluid at growth temperatures near 37C."


DOWNLOAD Powerpoint files ( ppt files)

How we learn (ppt) & Lecture 1:
Lecture 2: intro
Lecture 3: intro membranes
Lecture 4: neuro
Lecture 5: Sensory
Lecture 6: Muscle
Lecture 7: behavior
Lecture 8: endocrine

Clinical endocrine (ppt)

Lecture 9: circulation

04/03/2018- ppt before exam

Lecture 10: Respriation
Lecture 11: OSM and renal

Lecture GI

Lecture wrap up-temp



Just some more on Muscle ppt

Clinical heart stuff (ppt) ionic current in pacing PDF

 

 

Neat Information:

Muscle cramp and K + : http://www.ncbi.nlm.nih.gov/pubmed/23182013 " CONCLUSIONS: The effect of banana ingestion on EAMCs is unknown; however, these data suggested bananas are unlikely to relieve EAMCs by increasing extracellular [K(+)] or [glucose](p). The increases in [K(+)](p) were marginal and within normal clinical values. The changes in [K(+)](p), plasma K(+) content, and [glucose](p) do not occur quickly enough to treat acute EAMCs, especially if they develop near the end of competition."

..............................http://www.ncbi.nlm.nih.gov/pubmed/22157068..... Horses and hyperK diets http://www.ncbi.nlm.nih.gov/pubmed/10213428

Evolutionary Physiology 1994 (PDF)

.............PDF 1-Evol. Med PDF or MS WORD

................PDF 2- Ice Fish PDF or MS WORD

About Myelin (PDF1) & (PDF2)

About folic acid (pdf)

Male Brain (pdf)

Drug MDMA (ectasy) (PDF)

neg pH (pdf)

Imprint genes (pdf)

Music & Brain (pdf)

Kiss & Run (pdf)

Neat PDF on nerve gas agents (PDF)

The leech model and glia cells (PDF)

Muscle Growth (PDF)

Skeletal muscle fatigue (PDF)

Skeletal muscle (link to actin and myosin ratios....here)

Heart. MEA in rats PDF

 

 

STUDENT ACTIVITIES IN BIOLOGY

1. TRI- BETA

UK Beta Beta Beta Biology Honors Society

OVERHEADS used in class:

 

 

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