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FALL 2014 BIOLOGY 350- ANIMAL PHYSIOLOGY

Also check Black Board for updates and LAB CONTENT

GO TO LAB BIO350 web page

The lecture part of CLASS only meets on Tuesday & Thursdays

NEWS :http://uknow.uky.edu/content/uk-faculty-establish-american-physiological-society-kentucky-chapter-0 You can participate by presenting your undergrad research at the annual meeting .

Room 116 Biology - Lecture


OLD EXAMS (used in a summer course; MS Word 2003 format)

2006 summer Test 1, Test 2, Test 3, Test 4

2009 summer Test1, Test 2, Test 3, Test 4

On BB will be a master test bank for years of old exam questions

Back to teaching page

Fall 2014:

Biology Building

 

see this clip to get you thinking about course content:

https://www.youtube.com/watch?v=WVvKnq5XT-g

Instructor: But did you resubmit lab reports to earn back points?
Student: No, but I wanted to.

Instructor: Did you come by office hours to ask for help?
Student: No, but I was going to.

Instructor: Did you attend every lecture?
Student: I attended the important ones. Doesn't that count?

 

 

Lecture: Biological Sciences, Rm. 116
LABS: See Black Board for course ( Lab web pages from 2011 have some resources you might find of use)

The Bio 350 teaching lab is located in the Multidisciplinary Sciences Building (MDS) in room 155B. This is the red brick and stucco building directly across the street from Biology (Thomas Hunt Morgan Building), right next to the UK clinic parking garage. All laboratory sections of the BIO 350 course meet in MDS 155B .

TA's:Farid Yaghouby, Shreyas Joshi, and John Flunker

Labs:
Section 001: 9:00-11:50 Monday
Section 002: 12:00-14:50 Monday
Section 003: 15:00-17:50 Monday
Section 004: 9:00-11:50 Wednesday
Section 005: 12:00-14:50 Wednesday
Section 006: 15:00-17:50 Wednesday



Text book: It is listed in Kennedy's Book store under "Bio 350"

Title: Eckert Animal Physiology: Mechanisms and Adaptations, Fifth Edition, by David Randall, Warren Burggren, and Kathleen French.
http://www.whfreeman.com/newcatalog.aspx?isbn=0716738635

BIOLOGY 350- ANIMAL PHYSIOLOGY
Instructors:
Dr. Robin L. Cooper
RLCOOP1@email.uky.edu
Office: Morgan building-226
Tel: 257-5950
Office Hours: email for time
WWW Home page (go to)

Dr. Melody Danley
mlda227@uky.edu

Office: MDS 125

Office Hours: email for time

Teaching assistants for the course:

 

Farid Yaghouby

Sec 00?& 00?


Shreyas Joshi

Sec 00?& 00?

 

 

 

 

 

 

 

John Flunker

Sec 00?& 00?

 


Down load PDF files: Course outline PDF, MS word Chapter questions to focus on (go to)
Jump to on this page:

Course schedule (see below) (go to)

Download PPT files (go to)

COURSE OUTLINE

Biology 350

BIO350: Lecture Schedule for Bio 350, FALL 2014 (T & TH 9:30 AM- 10:45 AM)

Lecture, Day, Date, Topic Reading, Lecturer

1... Th... 8/28... Introduction to course and physiology...... Chapt 1&2, 3 (why comparative physiology-PDF-out 2014 today) (ECHO360)

Stress relaxation here and here

2...... T ...... 9/2...... Molecules, Energy and Biosynthesis ...... Chapt 3 (podcast, echo-360)

....... today we talked about COPD and O2 therapy (checkout this blog) and here is an Article (PDF)


3...... Th...... 9/4...... Membranes, Channels and Transport/ Physical basis of neuronal function...... Chapt. 4, & 5 (podcast, echo360)
4 ...... T...... 9/9...... Physical basis of neuronal function ...... Chapt. 5 (podcast, ..... echo 360)
5 ...... Th...... 9/11...... Physical basis of neuronal function & start on Chapter 6...... Ch. 5/6 (only echo 360)
6 ...... T...... 9/16...... Communication along and between neurons ...... Ch. 6
Chill out a bit with this here
(podcast and ECHO 360)

You can do it.... think of this mouse (here)

...... Th ...... 9/18...... Exam 1 ...... Ch1- 6 parts (adjustments made to EXAM 1 ....see PDF)

7...... T ...... 9/23...... Communication along and between neurons...... Ch. 6 (podcast and echo 360)
8 ...... Th ...... 9/25...... Communication along and between neurons ...... Ch. 6 (podcast and echo360)
9...... T ...... 9/30...... Sensory Mechanisms...... Ch. 7 (podcast did not record battery ran out, ECHO 360 works).
10 ...... Th ...... 10/2...... Sensory Mechanisms ...... Ch. 7 (
NO class, but here is podcast and ECHO 360)
11 ...... T ...... 10/7...... Sensory Mechanisms/ Organization of Nervous System ...... Ch. 7-8 (podcast and echo360- for some odd reason echo 360 stopped just as we started on chapter 8.... so go to podcast with your book in hand).
12 ...... Th ...... 10/9...... Muscle ...... Ch. 10 (podcast and Echo 360) muscle man Youtube Muscle man EMG music

Sibi Rajendran Google site is here https://sites.google.com/a/g.uky.edu/brain-imaging/


13 ...... T ...... 10/14...... Muscle & Behavior ...... Ch 10 (podcast and Echo360)
14 ...... Th ...... 10/16...... Muscle & Behavior...... Ch 10 & maybe Ch 11 (exam review)
(podcast and echo 360)

In case you need to chillout and relax from stress go here
...... T ...... 10/21...... Exam 2 ...... Ch 6-10 and maybe Ch 11 (except Ch 9)
15 ...... Th...... 10/23...... Behavior...... cont. Ch 11 (Oct. 24 at midnight your lecture assignment is due on safe assign through ......................................................................................... your black board) (podcast and Echo 360)
16 ...... T ...... 10/27...... Endocrine ...Hypothalamus-Pituitary ...... Chapt. 9 (
muscle topic ...ppt) (podcast and Echo 360)
17 ...... Th...... 10/30...... Thyroid, parathyroid, adrenal and pancreas ...... Chapt. 9 (podcast and Echo 360)
18 ...... T ...... 11/4...... Wrap up endocrine ...... Chapt. 9 (podcast and echo360)
19 ...... Th... 11/6...... Cardiovascular ...... Chapt. 12 (podcast and Echo 360)
20...... T ...... 11/11...... Cardiovascular ...... Chapt. 12 (fun cultural difference).
(Podcast and Echo360)

21 ...... Th ...... 11/13...... Cardiovascular / Respiration ...... Chapt. 12 & 13. If you are interested in heart development ppt

(Podcast and Echo360)

To relax this weekend you need to hear this music maybe some more as well here

...... T ...... 11/18...... Respiration ...... Chapt. 13 (11/3/2014, CHANGE IN SCHEDULE, NO class, but here is podcast and ECHO 360)
22 ...... Th ...... 11/20......
Exam 3 ...... 11, 9, 12, 13 (11/3/2014, CHANGE IN SCHEDULE)
23 ...... T ...... 11/25...... Respiration ...... Chapt. 13 (This day will be recorded in case you want to get on the road for the holiday. No points off for not coming to lecture) (Podcast and Echo360)

A very cool YouTube clip sent by your classmate: It is 4 minutes long and definitely a good watch. https://www.youtube.com/watch?v=YDspP4BhlTw

...... Th ...... 11/27...... Holiday - Thanksgiving
24...... T ...... 12/2...... Respiration / Ionic and Osmotic Balance
......Chapt. 13 &14 (Podcast and Echo360)
25 ......Th ......12/4......Ionic and Osmotic Balance ......Chapt. 14 (Podcast and Echo360)

Ion                         Normal blood concentration range (mmol.L−1)
Sodium                 135–145
Calcium                2.1–2.8
Potassium           ~ 3.5–5.0
Chloride               95–105
pH                          7.35-7.45
pCO2                     35-45
HCO3-                   22 to 26 mEq/liter ( some other sources 21–28 mEq/L)


26 ......T ......12/9......Ionic and Osmotic Balance/ Digestion ......Chapt. 14 &15 (Podcast and Echo360)
27 ......Th...... 12/11...... Digestion / Heat and adaptations ......Chapt. 15-17 ( gut brain connections) (current article on poop) (also drugs & the GUT)
(Podcast and Echo360)

Chill out a bit with this here  & have a good break here

 

A litte more chill'n here


.........Monday 12/15/14......FINAL EXAM @ 10:30 A.M-12:30 PM room 116 (http://www.uky.edu/registrar/content/final-exam-schedule-fall-2014)

 

BIO 350 Lab Schedule: See your black board page.

The outline presented above is a tentative plan for the semester. Specific topics and assignments are subject to change.

Principal Learning Objectives:
(Same learning objectives from http://courses.cit.cornell.edu/biog1440/)
1. To gain understanding of the principles of how animals work at the molecular, cellular, and systems levels. This understanding will come not by memorizing a large body of facts, but by developing mental models of the various physiological processes (e.g. transport processes, cell-cell signaling, metabolism, thermoregulation, circulation, respiration…) that underlie life.
2. To gain skill in thinking like a physiologist. This requires both asking and answering questions about physiology, and so involves observing phenomena, generating hypotheses about the underlying mechanisms, and devising tests of your hypotheses.
3. To appreciate the physiological similarities and differences between the physiologies of humans and other organisms, and so to understand how the study of physiology is thoroughly relevant to your own life and to the world around you.

Additional Lab Guidelines
An essential component of learning in physiology requires the use of live animals. It is impossible to demonstrate the full extent of possible responses through textbooks readings or lectures. As emerging professionals, it is expected that all students will demonstrate respect and maturity when working with these animals. If any disrespect or intentional cruelty is inflicted upon the animals, it may be reason to be expelled from the course with an "I" (incomplete), "W" (withdrawal), or automatic "E" (failing grade) depending the timing and degree of the offense.
No horse play, cutting up, playing around, etc. is allowed in the laboratory. There are many students coming and going in the lab throughout the day and materials are sometimes shuffled around. Squirting someone with a solution in a syringe or a bottle can be dangerous. You might "know" it is water but another person does not. A 3M KCl solution can easily be mistaken for water, and can be very harmful if squirted by accident in someone's eye.
We will use a fixative in the lab. The fix solution is a Bouin's solution (Prepared with saturated picric acid, formaldehyde and acetic acid; Sigma-Aldrich Co.). Some people are very allergic to the vapors of formaldehyde. If you know you are allergic please inform the instructor (Dr. Danley) as soon as possible so we can make alternative plans. The fix solution is to remain in the vented hood.
Every student will have to have completed the on line safety test and bring to the lab on the 1st day of your section meeting time. It is an easy test and you can take it multiple times until you get a 100 %. Either save and email your TA, or print it out and bring it to the first lab of the semester. The TA will check you off for having completed the exercise. The website for the safety test is:
http://ehs.uky.edu/classes/chemhyg/chemclass.php

Animal care:
Even though you will be using primarily invertebrate animals in these laboratories no torture of the animals is allowed. If any torturing occurs to the animals it is reason to be expelled from the course with an "I" (incomplete) or possible a "W" (withdrawal) depending the timing within the semester.
No horse play, cutting up, playing ball etc.. allowed in the laboratory period. Squirting someone with a solution in a syringe or a water bottle can be dangerous. You might know it is water but another person does not. 3M KCl can be very harmful if squirted by accident in someone's eye.
We will use a fixative in the lab. The fix solution is a Bouin's solution (Prepared with saturated picric acid, formaldehyde and acetic acid; Sigma-Aldrich Co.). Some people are very allergic to the vapors of formaldehyde. If you know you are allergic please inform the instructor (Dr. Cooper) as soon as possible so we can make alternative plans. The fix solution is to remain in the vented hood.


BIO 350 Laboratory Schedule

see lab web page

LABwww350FALL2014.htm


IMPORTANT ACADEMIC DATES (Fall 2014)

http://www.uky.edu/registrar/content/fall-2014-semester

 


Suggested questions at the end of each chapter

Ch. 1: Chapter 1: 1, 2

........PDF of text handed out in class

................PDF 1-Evol. Med PDF or MS WORD

................PDF 2- Ice Fish PDF or MS WORD

Look at oxidative stress paper (PDF)

Ch. 2: NA

Ch. 3: 8, 12, 13, 18, 19, 20, 21, 30

Lactate, not pyruvate, is neuronal aerobic glycolysis end product: an in vitro electrophysiological study. {PDF}

 

Ch. 4: 1, 10,11, 13, 15, 19

Ch. 5: 3, 4, 6. 9, 16, 19

Chapter 6: 2, 3 . Also fun sensory activities in lab as well as going over the exam.

Chapter 6: 7, 8, 12, 14, 18

Chapter 7:1, 2, 3, 7, 10, 14

Mean quantal content HW Handed out. See these if you loose the one in recitation: PDF , MS word or Gif file

Chapter 8: 3, 6, 9

Week of Oct 5 discuss [PDF4] & [PDF5]

Chapter 10: 1, 3, 6, 12, 19, 22

READ OVER : PDF 1, PDF 2

here is a general link (go to)

Chapter 11: 2, 13

You should be able to answer these questions (you might see them again) !

Reading: in chapter 9

Questions for recitation

1. Discuss the differences between autocine, paracrine, neurocrine and endocrine secretion.

2. What are pheromones?

3. Explain how catecholamines can have so many different actions.

4. Discuss examples that illustrate the intimate functional association of the nervous and endocrine systems.

5. How can a single second messenger, (e.g. cAMP or IP3) induced by binding of different hormones, mediate different cellular responses in different tissues?

6. Explain how a small number of hormone molecules can elicit cell responses involving millions of times as many molecules?

 

 

EXTRA Note:

To the issue about CHOLESTEROL and fluidity of biological membranes within normal temperatures. There maybe differences in the teaching on this point in Cell Biology and Animal Physiology so keep in mind which system, animal or bacteria, and the normal operating temperatures for the organisms.

In relation to Bio350 ANIMAL physiology and NOT bacterial cells the point is that cholesterol decreases fluidity in biological membranes of mammals.

Lets see the text by Lodish et al., (4th edition, 2000) Molecular Cell Biology

Page 165:

"Membrane cholesterol is another major determinate of bilayer fluidity....... The net effect of cholesterol on membrane fluidity varies, depending on the lipid composition. ...... At the high concentrations found in eukaryotic plasma membranes, cholesterol tends to make the membranes less fluid at growth temperatures near 37C."


DOWNLOAD Powerpoint files (as PDF files or ppt files)

Chapter 1-3 {ppt} {PDF}

Chapter 4 {ppt} {PDF}

Chapter 5 {ppt} {PDF}

Chapter 6 {ppt-a} {PDF-a}, {ppt-b} {PDF-b}

Chapter 7 {ppt-a} {PDF-a}, {ppt-b} {PDF-b}

Chapter 8 {ppt} {PDF}

Chapter 10 {ppt-a} {PDF-a}, {ppt-b} {PDF-b}

Chapter 11 (ppt) {PDF}

 

chapter 9 {ppt-a; ppt--b} {PDF-a; PDF-b}

Clinical endocrine (ppt) overhead used in class Jpeg PDF

Just some more on Muscle ppt

chapter 12 {ppt-a; ppt-b} {PDF-a; PDF-b}

Clinical heart stuff (ppt) ionic current in pacing PDF

chapter 13 {ppt-a; ppt-b} {PDF-a; PDF-b}

chapter 14 {ppt-a; ppt-b} {PDF-a; PDF-b}

chapter 15 {ppt-a; ppt-b} {PDF-a; PDF-b}

chapter 16 {ppt} {PDF}

chapter 17 {ppt} {PDF}

 

 

Neat Information:

Evolutionary Physiology 1994 (PDF)

About Myelin (PDF1) & (PDF2)

About folic acid (pdf)

Male Brain (pdf)

Drug MDMA (ectasy) (PDF)

neg pH (pdf)

Imprint genes (pdf)

Music & Brain (pdf)

Kiss & Run (pdf)

Neat PDF on nerve gas agents (PDF)

The leech model and glia cells (PDF)

 

 

STUDENT ACTIVITIES IN BIOLOGY

1. SPUR- Society for Promotion of Undergraduate Research.

It is a great new club for anyone in research, or who is interested in doing research.By the way, for those of you that were interested in getting a lab position, the first step is to fill out an application, the link below will take you directly to it. The application may seem long/unneccesary, but it is not a
selective process. Search under UK web site
"Society for Promotion of Undergraduate Research"

2. TRI- BETA

UK Beta Beta Beta Biology Honors Society

 

 

OVERHEADS used in class:

 

 

 

 

 

 

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