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FALL 2016 BIOLOGY 350- ANIMAL PHYSIOLOGY

Check Canvas and lab web page for updates and LAB CONTENT

GO TO LAB BIO350 web page

The lecture part of CLASS for sections 3, 4 and 5 meets on M, W and F

Room 116 Biology

Lecture M,W,F 10:00 -10:50 AM (sections 3, 4, & 5)


OLD EXAMS (used in a summer course; MS Word 2003 format)

2006 summer Test 1, Test 2, Test 3, Test 4

2009 summer Test1, Test 2, Test 3, Test 4

On Canvas will be a master test bank for years of old exam questions

Back to teaching page

Fall 2016:

Biology Building

 

see this clip to get you thinking about course content:

https://www.youtube.com/watch?v=WVvKnq5XT-g

Instructor: But did you resubmit lab reports to earn back points?
Student: No, but I wanted to.

Instructor: Did you come by office hours to ask for help?
Student: No, but I was going to.

Instructor: Did you attend every lecture?
Student: I attended the important ones. Doesn't that count?

 

 

Lecture: Biological Sciences, Rm. 116
LABS: See Black Board for course ( Lab web pages from 2011 have some resources you might find of use)

The Bio 350 teaching lab is located in the new Academic Science Building

TA's:

Labs for sections 3-5:
Section 003: Academic Science Building, room 104, 15:00 to 17:50 Monday
Section 004: Academic Science Building, room 104, 12:00-14:50 Wednesday
Section 005: Academic Science Building, room 104, 15:00-17:50 Wednesday

Text book: It is listed in Kennedy's Book store under "Bio 350"

Title: Animal Physiology: From Genes to Organisms, 2nd Edition
Lauralee Sherwood | Hillar Klandorf | Paul Yancey
ISBN-13: 9780840068651
© 2013 | Published

The discounted ISBN for the ebook and LooseLeaf text are below. Sherwood/Klandorf/ 2nd ©2016 
Animal Physiology-LL 978133705462- $126 Mindtap Reader Ebook in Canvas:SHERWOOD/KLANDORF... 2nd ©2013  9781133001249 - $116

http://www.cengage.com/


BIOLOGY 350- ANIMAL PHYSIOLOGY
Instructors:
Dr. Robin L. Cooper
RLCOOP1@email.uky.edu
Office: Morgan building-226
Tel: 257-5950
Office Hours: email for time
WWW Home page (go to)

Dr. Melody Danley
mlda227@uky.edu

Office: 153 C, NEW ACADEMIC SCI BUILDING

Office Hours: email for time

Teaching assistants for the course:

Cole Malloy

camall2@uky.edu


Nadera Dabbain

Nida222@g.uky.edu

 

 

 

 

 

 

 

Victoria Thompson

tori.thompson@uky.edu

 

Jeffrey Chalfant

jeffrey.chalfant@uky.edu


Down load PDF files: Course outline PDF, MS word  
Jump to on this page:

Course schedule (see below) (go to)

Download PPT files (go to)

COURSE OUTLINE

Biology 350

BIO350: Lecture Schedule for Bio 350, FALL 2016 Sections 3, 4 & 5 (Lecture 10:00 -10:50 AM on M, W and F)

1...8/24 ... Lecture 1: Overview of class: lecture+ lab, exams etc; How one learns.
.............Homeostasis, Krogh principle, + and - feedback, overview of all systems,
.............(Chapter 1 in Sherwood) (why comparative physiology-PDF) (podcast, ECHO360-Audio only see ppt files)

.............Stress relaxation here and here

2.....8/26.......Lecture 2: continue with Homeostasis. Cellular energy: ATP from glucose, comparative-anoxic
.............Animals. Cells and molecules (Chapter 1 & 2 in Sherwood) (podcast , echo-360)
Movie

....... about COPD and O2 therapy (checkout this blog) and here is an Article (PDF)

3......8/29........... Lecture 3: Cont. Cellular energy: ATP from glucose, comparative-anoxic
.............Animals. Cells and molecules (Chapter 2 in Sherwood) (podcast , echo360)

4 ......8/31 ......Lecture 4: membrane physiology, membranes, Na/K ATPase, membrane potential (Ch 3 &4) (podcast, ..... ............echo 360) http://helmont1.tripod.com/hersheypsb49-3.htm

5 ......9/2 .......Lecture 5: membrane physiology, membranes, Na/K ATPase, membrane potential (Ch 3 &4) (Podcast, echo .............360-screwed up because I used the web cam to show the larval heart beating.... see podcast and ppt files)

9/5, Labor Day - Academic Holiday

6 ......9/7 ...... Lecture 6: APs, graded potentials, summation, V-gated Na and K channels-gates (Ch 3 &4) Chill out a bit with this here (podcast and ECHO 360)

7......9/9 ....... Lecture 7: Continue Aps, graded potentials etc (Ch 3 &4) (podcast and echo 360)
8 ......9/12 ...... Lecture 8: Anatomy of neuron, squid giant axon vs mammalian neurons, phasic and tonic responses, types ......................of synapses (Ch 4) (podcast and echo360)
9......9/14 .......Lecture 9: types of synapses, neuromuscular junction (Ch 4) (podcast, ECHO 360 ).
10 .....9/16. ...... Lecture 10: types of synapses, NMJ & Nervous systems (Ch 4 & 5) (podcast and ECHO 360) (lecture assignment PDF)
11 ......9/19...... Lecture 11: Nervous systems, CNS, PNS, ANS, comparative, mammalian brain, Neurotransmitters
.............(Ch 4 & 5) (podcast and echo360). Here is the Prozac paper [PDF]
12 ......9/21 ....... Lecture 12: Neurotransmitters, Sensory mechanisms (Ch 5 & 6) (podcast and Echo 360)
Paper on invertebrate ANS [PDF- provided for your sleeping pleasure]

13 ......9/23...... Lecture 13: Sensory mechanisms & behavior. (Ch 5 & 6) (podcast and Echo360)
14 .....9/26........ Lecture 14: Sensory mechanisms & behavior. (Ch 5 & 6) (podcast and Echo360)

In case you need to chillout and relax from stress go here

15 ......9/28........ Lecture 15: Catch up & Exam review (? at midnight your lecture assignment is due on safe assign through your Canvas log in )(podcast,and Echo360) QUIZ DAY !!!!!!!!!!!!!!!!

You can do it.... think of this mouse (here)

9/30: EXAM 1 (FRIDAY) - Multiple choice, short answer and open responses. (Exam Key PDF posted here)

..................Muscle man Youtube Muscle man EMG music (muscle topic ...ppt)

16 ......10/3 ....... Lecture 16: Muscle physiology (Ch 8) (podcast and Echo360)
17 ......10/5 ..... Lecture 17: Muscle physiology (Ch 8) (podcast and Echo360 darn computer only recorded audio, see ppt)
18 ......10/7 ...... Lecture 18: Muscle physiology (Ch 8) (podcast and Echo360)
19 ......10/10...... Lecture 19: Endocrine: Intro, (Ch 7) (podcast and Echo360)
20......10/12 ....... Lecture 20: Endocrine: Growth, Adrenal (Ch 7) (podcast and Echo360)
STILL ON MUSCLE

21 .....10/14...... Lecture 21: Endocrine: thyroids (Ch 7) (podcast-1, Podcast-2, Echo360-1, Echo360-2).

...............To relax this weekend you need to hear this music maybe some more as well here

22 .....10/17. ......., Lecture 22: Endocrine: fuel metabolism, energy balance (Ch 7).
................AND Thermal physiology (Chapter 15) (podcast and Echo360
)

...............Oct 10-21, midterm grading window

23 ......10/19 ..... Lecture 23: Endocrine (Ch 7) (podcast and Echo360) QUIZ day in class

CATCH UP PODCAST-part 2 & ECHO360-part 2 on ENDOCRINE...... NEED TO LOOK OVER FOR THE CONTENT TO BE TESTED ON.

If you are interested in medical endrocrinology but also to help reinforce the endocrine content which we cover in class see this series of ppt slides (PPT)

A very cool YouTube clip sent by your last year classmate: It is 4 minutes long and definitely a good watch. https://www.youtube.com/watch?v=YDspP4BhlTw

If you are interested in heart development ppt

24......10/21....... Lecture 24: Cardiovascular (Ch 9) (podcast and Echo360)
25 ......10/24...... Lecture 25: Cardiovascular & Respiration (Ch 9 & 11) (podcast and Echo360)

http://www.ekgusa.com/ceol/abgmap/bgmodul/cebgquiz/bgmapqc.htm

Ion                         Normal blood concentration range (mmol.L−1)
Sodium                 135-145
Calcium                2.1-2.8
Potassium           ~3.5-5.0
Chloride               95-105
pH                          7.35-7.45
pCO2                     35-45
HCO3-                   22 to 26 mEq/liter ( some other sources 21–28 mEq/L)


26 ......10/26.....Lecture 26: Respiration (Ch 9 & 11) (podcast and Echo360)
27 .....10/28 ....... Lecture 27: Respiration (Ch 9& 11) (podcast and Echo360)

The part I drew out today was :
https://en.wikipedia.org/wiki/Einthoven%27s_triangle
http://courses.kcumb.edu/physio/ecg%20primer/ecgaxis.htm

28.....10/31....... Lecture 28: Respiration (Ch 11) (podcast-Part A & Part B and Echo360-Part A & Part B)

29.....11/2..... Lecture 29: Catch up & Exam review (podcast and Echo360) QUIZ DAY

11/4, EXAM 2 (FRIDAY) - Multiple choice, short answer and open responses.

( I handed back the exams with the key for you to double check. KEY-PDF )

30.....11/7....... Lecture 30: Excretion, fluid and ionic/osmotic balance (Ch 11 & 12 & 13) (podcast and Echo360)

31.....11/9....... Lecture 31: Excretion, fluid and ionic/osmotic balance (Ch 12 & 13) (podcast and Echo360)

32.....11/11....... Lecture 32: Excretion, fluid and ionic/osmotic balance (Ch 12 & 13) (podcast and Echo360)

Chill out a bit with this here  & have a good break here

A litte more chill'n here

33.....11/14....... Lecture 33: Excretion, fluid and ionic/osmotic balance (Ch 12 & 13) (podcast and Echo360)

34.....11/16....... Lecture 34: Excretion, fluid and ionic/osmotic balance (Ch 12 & 13) (podcast and Echo360)

( gut brain connections) (current article on poop) (also drugs & the GUT)

35.....11/18....... Lecture 35: Digestion (Ch 12 &13) (podcast and Echo360)

36.....11/21....... Lecture 36:Digestion (Ch 12 & Ch13)) (podcast and Echo360)

11/23, No class, Thanksgiving

37.....11/28....... Lecture 37: Digestion (Ch 13 & 14) (podcast and Echo360)

38.....11/30....... Lecture 38: Reproduction (Ch 14 & 16) (podcast and Echo360)

39.....12/2....... Lecture 39: Reproduction (Ch 16) (podcast Part 1....Part 2 and Echo360 part 1 ... part 2) QUIZ DAY

40.....12/5....... Lecture 40: Reproduction (Ch 16) (podcast and Echo360) QUIZ DAY

41.....12/7....... Lecture 41: Catch up on content (podcast and Echo360)

42.....12/9....... Lecture 42: Review for final exam (podcast and Echo360)

...................................................Important link for relaxation https://www.youtube.com/watch?v=JNS_SUmCJm4

FINAL EXAM: Monday 12/12/16 at 8:00 AM Room 116

Cumulative with emphasis on 3rd section of class

http://www.uky.edu/registrar/content/fall-final-exam-schedule

 

BIO 350 Lab Schedule: See your black board page.

The outline presented above is a tentative plan for the semester. Specific topics and assignments are subject to change.

Principal Learning Objectives:
(Same learning objectives from http://courses.cit.cornell.edu/biog1440/)
1. To gain understanding of the principles of how animals work at the molecular, cellular, and systems levels. This understanding will come not by memorizing a large body of facts, but by developing mental models of the various physiological processes (e.g. transport processes, cell-cell signaling, metabolism, thermoregulation, circulation, respiration…) that underlie life.
2. To gain skill in thinking like a physiologist. This requires both asking and answering questions about physiology, and so involves observing phenomena, generating hypotheses about the underlying mechanisms, and devising tests of your hypotheses.
3. To appreciate the physiological similarities and differences between the physiologies of humans and other organisms, and so to understand how the study of physiology is thoroughly relevant to your own life and to the world around you.

Additional Lab Guidelines
An essential component of learning in physiology requires the use of live animals. It is impossible to demonstrate the full extent of possible responses through textbooks readings or lectures. As emerging professionals, it is expected that all students will demonstrate respect and maturity when working with these animals. If any disrespect or intentional cruelty is inflicted upon the animals, it may be reason to be expelled from the course with an "I" (incomplete), "W" (withdrawal), or automatic "E" (failing grade) depending the timing and degree of the offense.
No horse play, cutting up, playing around, etc. is allowed in the laboratory. There are many students coming and going in the lab throughout the day and materials are sometimes shuffled around. Squirting someone with a solution in a syringe or a bottle can be dangerous. You might "know" it is water but another person does not. A 3M KCl solution can easily be mistaken for water, and can be very harmful if squirted by accident in someone's eye.

Every student will have to have completed the on line safety test and bring to the lab on the 1st day of your section meeting time. It is an easy test and you can take it multiple times until you get a 100 %. Either save and email your TA, or print it out and bring it to the first lab of the semester. The TA will check you off for having completed the exercise. The website for the safety test is:

http://ehs.uky.edu/authenticate.php

Animal care:
Even though you will be using primarily invertebrate animals in these laboratories no torture of the animals is allowed. If any torturing occurs to the animals it is reason to be expelled from the course with an "I" (incomplete) or possible a "W" (withdrawal) depending the timing within the semester.
No horse play, cutting up, playing ball etc.. allowed in the laboratory period. Squirting someone with a solution in a syringe or a water bottle can be dangerous. You might know it is water but another person does not. 3M KCl can be very harmful if squirted by accident in someone's eye.
We will use a fixative in the lab. The fix solution is a Bouin's solution (Prepared with saturated picric acid, formaldehyde and acetic acid; Sigma-Aldrich Co.). Some people are very allergic to the vapors of formaldehyde. If you know you are allergic please inform the instructor (Dr. Cooper) as soon as possible so we can make alternative plans. The fix solution is to remain in the vented hood.


BIO 350 Laboratory Schedule

see lab web page

LABwww350FALL2016.htm


IMPORTANT ACADEMIC DATES (Fall 2016)

http://www.uky.edu/registrar/content/fall-2016-semester

 


Suggested questions at the end of each chapter

Ch. 1: Chapter 1: 1, 2

 

................PDF 1-Evol. Med PDF or MS WORD

................PDF 2- Ice Fish PDF or MS WORD

Look at oxidative stress paper (PDF)

 

 

 

 

 

EXTRA Note:

To the issue about CHOLESTEROL and fluidity of biological membranes within normal temperatures. There maybe differences in the teaching on this point in Cell Biology and Animal Physiology so keep in mind which system, animal or bacteria, and the normal operating temperatures for the organisms.

In relation to Bio350 ANIMAL physiology and NOT bacterial cells the point is that cholesterol decreases fluidity in biological membranes of mammals.

Lets see the text by Lodish et al., (4th edition, 2000) Molecular Cell Biology

Page 165:

"Membrane cholesterol is another major determinate of bilayer fluidity....... The net effect of cholesterol on membrane fluidity varies, depending on the lipid composition. ...... At the high concentrations found in eukaryotic plasma membranes, cholesterol tends to make the membranes less fluid at growth temperatures near 37C."


DOWNLOAD Powerpoint files (as PDF files or ppt files)

How we learn (ppt)

8/24, Lecture 1: (ppt)
8/26, Lecture 2: (ppt)
8/29, Lecture 3: Same stuff above
8/31, Lecture 4: Same stuff above
9/2, Lecture 5: (chapter 3, ppt-A)

http://www.pnas.org/content/105/48/18770.long

9/5, Labor Day - Academic Holiday
9/7, Lecture 6: Chapter 3, ppt-B
9/9, Lecture 7:
9/12, Lecture 8:
9/14: Lecture 9:Chapter 4 ppt
9/16: Lecture 10:
9/19: Lecture 11: Chapter 5 ppt -neuro

Notes made in class (PDF-1, PDF-2)


9/21: Lecture 12:
9/23: Lecture 13: Chapter 6 ppt-sensory
9/26: Lecture 14:
9/28: Lecture 15:

9/30: EXAM 1 (FRIDAY) - Multiple choice, short answer and open responses.

10/3, Lecture 16:
10/5, Lecture 17: Chapter 8 ppt- muscle
10/7, Lecture 18:
10/10, Lecture 19:

10/12, Lecture 20: Chapter 7-Endocrine
10/14, Lecture 21:
10/17, Lecture 22:

Oct 10-21, midterm grading window

10/19, Lecture 23: Chapter 9- ...................................circulation
10/21, Lecture 24:
10/24, Lecture 25:
10/26, Lecture 26:
10/28 Lecture 27:
10/31, Lecture 28:
11/2, Lecture 29:
Chapter 11-Respiration

11/4, EXAM 2 (FRIDAY) - Multiple choice, short answer and open responses possible.

11/7, Lecture30:

11/9, Lecture 31:
11/11, Lecture 32:
11/14, Lecture 33:osm-regulation ppt
11/16, Lecture 34:
11/18, Lecture 35: Chapter 13-ion balance ppt
11/21, Lecture 36:

11/23, No class, Thanksgiving

11/28, Lecture 37: Chapter 14 Digestion ppt
11/30, Lecture 38:
12/2, Lecture 39:
12/5, Lecture 40: Chapter 16 on Reproduction ppt
12/7, Lecture 41: Wrap up ppts-whole animal
12/9, Lecture 42:
Review

Clinical endocrine (ppt) overhead used in class Jpeg PDF

Just some more on Muscle ppt

Clinical heart stuff (ppt) ionic current in pacing PDF

 

 

 

 

Neat Information:

Muscle cramp and K + : http://www.ncbi.nlm.nih.gov/pubmed/23182013 " CONCLUSIONS: The effect of banana ingestion on EAMCs is unknown; however, these data suggested bananas are unlikely to relieve EAMCs by increasing extracellular [K(+)] or [glucose](p). The increases in [K(+)](p) were marginal and within normal clinical values. The changes in [K(+)](p), plasma K(+) content, and [glucose](p) do not occur quickly enough to treat acute EAMCs, especially if they develop near the end of competition."

..............................http://www.ncbi.nlm.nih.gov/pubmed/22157068..... Horses and hyperK diets http://www.ncbi.nlm.nih.gov/pubmed/10213428

Evolutionary Physiology 1994 (PDF)

.............PDF 1-Evol. Med PDF or MS WORD

................PDF 2- Ice Fish PDF or MS WORD

About Myelin (PDF1) & (PDF2)

About folic acid (pdf)

Male Brain (pdf)

Drug MDMA (ectasy) (PDF)

neg pH (pdf)

Imprint genes (pdf)

Music & Brain (pdf)

Kiss & Run (pdf)

Neat PDF on nerve gas agents (PDF)

The leech model and glia cells (PDF)

Muscle Growth (PDF)

Skeletal muscle fatigue (PDF)

Skeletal muscle (link to actin and myosin ratios....here)

Heart. MEA in rats PDF

 

 

STUDENT ACTIVITIES IN BIOLOGY

1. SPUR- Society for Promotion of Undergraduate Research.

It is a great new club for anyone in research, or who is interested in doing research.By the way, for those of you that were interested in getting a lab position, the first step is to fill out an application, the link below will take you directly to it. The application may seem long/unneccesary, but it is not a
selective process. Search under UK web site
"Society for Promotion of Undergraduate Research"

2. TRI- BETA

UK Beta Beta Beta Biology Honors Society

 

 

OVERHEADS used in class:

 

 

 

 

 

 

 

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