This course examines the gross as well as microscopic structural
properties and the physiological function of skeletal muscle. Students
will gain in-depth knowledge about not only normal muscle function,
but also about the adaptability and plasticity of skeletal muscle
under different environmental circumstances. The structure and function
of skeletal muscle as it relates to human health-related issues
will be examined and discussed.
Student Learning Outcomes
By the end of this course, students should be able to:
1. Have a conceptual understanding of muscle structure and function
and limitations that are shaped by their evolutionary history as
assessed by examination.
2. Understand the physiological function of muscles
3. Illustrate how muscles can be studied experimentally
4. Critically analyze research papers in the field of muscle biology
5. Discuss and develop new ideas and suggest future research directions
in the field of muscle biology.
The goals of this course are that the learning outcomes will be
met by the students
Requirements: The course will be a mix of lecture and student-led
discussion. Readings will be taken from the text and from the primary
research literature. The instructors will provide greater detail
on the term paper, but basically a student will read recent primary
research papers on one subject and will explain their meaning and
how the topics relates the field in muscle biology.
First draft- 25 pts
Final version -100 pts
(questions in class, paper discussions, online discussions)- 25
EXAMs- 100 pts each = 300 pts
a primary research article or research of a muscle disease or comparative
muscle review (<500 word article for the public, i.e. newspaper
or magazine)- 10 points
(ppt file or some sort of effective means of commutating the content)
- 20 points. This will be a individual assignment of presenting
the research paper that one has chosen to write about. This will
be a 7 minute class room presentation with 3 minutes of question
time to follow. The presentation will be towards the end of the
course. Student participation in the question period is encouraged.
will be provided with a Midterm Evaluation (by the midterm date)
of course performance based on criteria in syllabus
will be based on total points earned and will be assigned as follows:
A = 90 - 100 %
B = 80 - 89.99 %
C = 70 - 79.99 %
D = 60 - 69.99 %
E = less than 60 %
type report: Write a <500 word article for the public, i.e. newspaper
article/term paper: There will be one formal manuscript write-up
due this semester. The manuscript is intended to mimic the review
manuscript writing and submission processes required for scientific
publication, and it will utilize results from reviewing scientific
literature. The manuscript must be written independently (no group
submissions). The draft and final submission dates are listed above
in class schedule. The writing format described by the Journal of
Comparative Biochemistry and Physiology - Part A: Molecular &
Integrative Physiology will be used or Annual Reviews in Physiology.
As an example, go to the journal's web page and look up information
for authors at: http://www.elsevier.com/wps/find/journaldescription.cws_home/525464/description
The "guide to authors" provided by the journal provides
the formatting guidelines that must be followed for this assignment.
Additional information for this assignment will be made available
through the course website.
hours: Course Director has an open door policy, so feel free
to stop by the office any time to ask questions, or to clarify something
from class or the reading materials. However, when otherwise occupied
a meeting should be set up. All other instructors are available
by appointment also. It might be useful to form study groups and
study together regularly and formulate questions early.
the exams: The exams will allow you to demonstrate your understanding
of the material presented in class and in the textbook. Each exam
will last 60 min and will involve short answers of a few sentences
and/or diagrams and/or multiple choice questions and/or essay questions.
Make-up quizzes are given only in cases that are documented by a
medical excuse, and by notification of the instructor before administration
of the exam. Unexcused absence from an exam or failure to notify
the instructor prior to the quiz will result in a score of zero
for that exam. All make-up quizzes must be completed within one
week of the scheduled exam date. Missing more than one quiz will
result in a failing grade.
A grade of incomplete (INC) can only be given if a major portion
of the course has been completed at a passable level. An INC grade
will not be given for poor performance or for lack of attendance.
Documentation is required to justify a grade of INC. See the University
catalog or schedule of classes for information on withdrawal from
Course announcements, assignments, lecture outlines and additional
materials will be posted online using Blackboard. Exams and homework
dates will remain fixed. Updates to this syllabus (regarding topics
and reading) will be posted; please check periodically. You will
also receive important course announcements via your UK e-mail account.
If you do not use your UK e-mail account, you need to activate it.
It is strongly recommended that you check your e-mail regularly.
Instructors may send messages-sometimes with attachments-to the
class using this medium. You should also feel free to e-mail instructors
if you have any questions or problems. Feel free to call Dr. Dupont-Versteegden
as well, if you prefer a more personal communication or set up an
If you have a documented disability that requires academic accommodations,
please see instructors as soon as possible during scheduled office
hours. In order to receive accommodations in this course, you must
provide me with a Letter of Accommodation
from the Disability Resource Center (Room 2, Alumni Gym, 257?2754,
firstname.lastname@example.org) for coordination of campus disability services
available to students with disabilities.
Students need to notify the professor of absences prior to class
when possible. S.R. 188.8.131.52 defines the following as acceptable
reasons for excused absences: (a) serious illness, (b) illness or
death of family member, (c) University-related trips, (d) major
religious holidays, and (e) other circumstances found to fit "reasonable
cause for nonattendance" by the professor.
anticipating an absence for a major religious holiday are responsible
for notifying the instructor in writing of anticipated absences
due to their observance of such holidays no later than the last
day in the semester to add a class. Information regarding dates
of major religious holidays may be obtained through the religious
liaison, Mr. Jake Karnes (859-257-2754).
are expected to withdraw from the class if more than 20% of the
classes scheduled for the semester are missed (excused or unexcused)
per university policy.
Verification of Absences
Students may be asked to verify their absences in order for them
to be considered excused. Senate Rule 184.108.40.206 states that faculty
have the right to request "appropriate verification" when
students claim an excused absence because of illness or death in
the family. Appropriate notification of absences due to university-related
trips is required prior to the absence.
You must abide by UK's Code of Conduct (http://www.uky.edu/StudentAffairs/Code/index.html),
1. Academic dishonesty and impropriety, including plagiarism and
2. Interfering or attempting to interfere with or disrupting the
conduct of classes or any other normal or regular activities of
Per university policy, students shall not plagiarize, cheat, or
falsify or misuse academic records. Students are expected to adhere
to University policy on cheating and plagiarism in all courses.
The minimum penalty for a first offense is a zero on the assignment
on which the offense occurred. If the offense is considered severe
or the student has other academic offenses on their record, more
serious penalties, up to suspension from the university may be imposed.
and cheating are serious breaches of academic conduct. Each student
is advised to become familiar with the various forms of academic
dishonesty as explained in the Code of Student Rights and Responsibilities.
Complete information can be found at the following website: http://www.uky.edu/Ombud.
A plea of ignorance is not acceptable as a defense against the charge
of academic dishonesty. It is important that you review this information
as all ideas borrowed from others need to be properly credited.
II of Student Rights and Responsibilities (available online http://www.uky.edu/StudentAffairs/Code/part2.html)
states that all academic work, written or otherwise, submitted by
students to their instructors or other academic supervisors, is
expected to be the result of their own thought, research, or self-expression.
In cases where students feel unsure about the question of plagiarism
involving their own work, they are obliged to consult their instructors
on the matter before submission.
students submit work purporting to be their own, but which in any
way borrows ideas, organization, wording or anything else from another
source without appropriate acknowledgement of the fact, the students
are guilty of plagiarism. Plagiarism includes reproducing someone
else's work, whether it be a published article, chapter of a book,
a paper from a friend or some file, or something similar to this.
Plagiarism also includes the practice of employing or allowing another
person to alter or revise the work which a student submits as his/her
own, whoever that other person may be.
Students may discuss assignments among themselves or with an instructor
or tutor, but when the actual work is done, it must be done by the
student, and the student alone. When a student's assignment involves
research in outside sources of information, the student must carefully
acknowledge exactly what, where and how he/she employed them. If
the words of someone else are used, the student must put quotation
marks around the passage in question and add an appropriate indication
of its origin. Making simple changes while leaving the organization,
content and phraseology intact is plagiaristic. However, nothing
in these Rules shall apply to those ideas which are so generally
and freely circulated as to be a part of the public domain (Section
note: Any assignment you turn in may be submitted to an electronic
database to check for plagiarism.