Lab

CV

Home-country (South Korea)

etc.

Junyoung Lee

M.S Candidate

University of Kentucky

Department of Biology

Mentor: Dr. Robin L. Cooper

Research:

I am struggling with NMJ of Drosophila larva and crayfish in the lab to understand the properties of synaptic transmission.

Drosophila larva:

With the neuromuscular junction (NMJ), I am investigating the effects of kainate action on both pre- and post synaptic receptors. the molecular sequence of the glutamate receptor on muscle in drosophila NMJ is similar to the kainate/AMPA receptor in verterbrate. Pharmacologically, however, it shows the differenct action for kainate.

If you are interested in what is happening, just click Here.

Crayfish:

With the NMJ of crayfish walking leg, I suggest that there are at least two kinetic and distinguished vesicle pools within the presynaptic nerve terminal of the crayfish.

For this, I use the glutamate uptake blocker, DL-TBOA(dl-threo-beta-benzyloxyasparate) and serotonin (5-HT).

In the next step, I will use the bafilomysinn A which blocks the uptake of glutamate into vesicles.

For what???

As you cannot stop your finger from clicking Here, just let it go.