Biology 425
“Ecological Immunology”
The Ecology of Immune Function
Mondays 1:00-1:50
Rm 305, THM
Instructor: David F. Westneat
Office: Rm 105, MDR#3
Office hrs: Conferences with me are welcome; please contact me to schedule a time
Phone: 323-9499. E-mail: biodfw@uky.edu
Schedule
|
Week |
Reading (available online from UK computer) |
Presenter |
|
1: 23 Jan |
Introduction: What is Ecological Immunology? |
Westneat |
|
2: 30 Jan |
Sheldon BC, Verhulst S. 1996. Ecological immunology: Costly parasite defences and trade-offs in evolutionary ecology. TRENDS IN ECOLOGY & EVOLUTION 11 (8): 317-321. |
|
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3: 6 Feb |
Reusch TBH, et al. 2001. Female sticklebacks count alleles in a strategy of sexual selection explaining MHC polymorphism. NATURE 414 (6861): 300-302 |
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4: 13 Feb |
WEDEKIND C, et al. 1995. MHC-dependent mate preferences in humans. PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES B 260 (1359): 245-249. |
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5: 20 Feb |
Ekblom R, et al. 2005. Female choice and male humoral immune response in the lekking great snipe (Gallinago media). BEHAVIORAL ECOLOGY 16 (2): 346-351. |
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|
6: 27 Feb |
Lindstrom K,
Lundstrom J. 2000. Male greenfinches (Carduelis chloris) with brighter
ornaments have higher virus infection clearance rate. |
|
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7: 6 March |
Fedorka KM, Zuk M 2005. Sexual conflict and female immune suppression in the cricket, Allonemobious socius. JOURNAL OF EVOLUTIONARY BIOLOGY 18 (6): 1515-1522. (available from instructor) |
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8: 13 March |
No Class: Spring Break |
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9: 20 March |
Zuk M, Stoehr AM. 2002.
Immune defense and host life history |
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10: 27 March |
Gwynn DM, et al. 2005. Resistance is costly: trade-offs between immunity, fecundity and survival in the pea aphid. PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES 272 (1574): 1803-1808. |
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11: 3 April |
No Class |
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12: 10 April |
Ardia DR, et al. 2003.Reproductive effort reduces long-term immune function in breeding tree swallows (Tachycineta bicolor). PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES B 270 (1525): 1679-1683. |
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13: 17 April |
Haussmann MF, et al.
2005. Cell-mediated immunosenescence in birds |
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14: 23 April |
Helle S, Lummaa V, Jokela J 2004. Accelerated immunosenescence in preindustrial twin mothers. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES USA 101 (33): 12391-12396. |
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Class Procedures: Biology 425 is a course designed to introduce students to methods of thinking critically about conceptual hypotheses and the data that address them in a focused area. Each week the class will read an article, either a review or a primary scientific paper, and discuss it. Discussion will be lead by a member of the class. The goal of discussions are twofold: 1) to ensure understanding of hypotheses and how they were evaluated by asking questions and attempting answers, and 2) to learn how an existing study can lead to new hypotheses or ideas that need testing.
Grading.- Discussion is the focus of this course. Hence grades will be based on three components. 1. How well you lead the discussion (100 pts). The discussion leader should give a summary of the paper and the ideas it addresses, and then solicit questions/discussion from the class. Good discussion leaders also mediate and guide the discussion. 2. Attendance (100 pts). Given the goals of the class, attending and being prepared is critical. I will allow two excused absences without penalty, but additional absences will have an effect on the grade. If students are having difficulty attending, please talk to the instructor as alternative assignments may be possible. 3. Participation (100 pts). To ensure that all students are prepared to participate, each week everyone will turn in a 1 paragraph summary of the reading and 4 questions they had about the material. Students who actually ask these questions in class or offer answers to other students’ questions will score extra points.
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