Biology 425

“Ecological Immunology”

The Ecology of Immune Function

Mondays 1:00-1:50

Rm 305, THM

 

Instructor: David F. Westneat

Office: Rm 105, MDR#3

Office hrs: Conferences with me are welcome; please contact me to schedule a time

Phone: 323-9499. E-mail: biodfw@uky.edu

Schedule

Week

Reading (available online from UK computer)

Presenter

1: 23 Jan

Introduction: What is Ecological Immunology?

Westneat

2: 30 Jan

Sheldon BC, Verhulst S. 1996. Ecological immunology: Costly parasite defences and trade-offs in evolutionary ecology. TRENDS IN ECOLOGY & EVOLUTION 11 (8): 317-321.

 

3: 6 Feb

Reusch TBH, et al. 2001. Female sticklebacks count alleles in a strategy of sexual selection explaining MHC polymorphism. NATURE 414 (6861): 300-302

 

4: 13 Feb

WEDEKIND C, et al. 1995. MHC-dependent mate preferences in humans. PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES B 260 (1359): 245-249.

 

5: 20 Feb

Ekblom R, et al. 2005. Female choice and male humoral immune response in the lekking great snipe (Gallinago media). BEHAVIORAL ECOLOGY 16 (2): 346-351.

 

6: 27 Feb

Lindstrom K, Lundstrom J. 2000. Male greenfinches (Carduelis chloris) with brighter ornaments have higher virus infection clearance rate.
BEHAVIORAL ECOLOGY AND SOCIOBIOLOGY 48 (1): 44-51.

 

7: 6 March

Fedorka KM, Zuk M 2005. Sexual conflict and female immune suppression in the cricket, Allonemobious socius. JOURNAL OF EVOLUTIONARY BIOLOGY 18 (6): 1515-1522. (available from instructor)

 

8: 13 March

No Class: Spring Break

 

9: 20 March

Zuk M, Stoehr AM. 2002. Immune defense and host life history 
AMERICAN NATURALIST 160: S9-S22

 

10: 27 March

 Gwynn DM, et al. 2005. Resistance is costly: trade-offs between immunity, fecundity and survival in the pea aphid. PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES 272 (1574): 1803-1808.

 

11: 3 April

No Class

 

12: 10 April

Ardia DR, et al. 2003.Reproductive effort reduces long-term immune function in breeding tree swallows (Tachycineta bicolor). PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES B 270 (1525): 1679-1683.

 

13: 17 April

Haussmann MF, et al. 2005. Cell-mediated immunosenescence in birds 
OECOLOGIA 145 (2): 270-275.

 

14: 23 April

Helle S, Lummaa V, Jokela J 2004. Accelerated immunosenescence in preindustrial twin mothers. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES USA 101 (33): 12391-12396.

 

 

Class Procedures: Biology 425 is a course designed to introduce students to methods of thinking critically about conceptual hypotheses and the data that address them in a focused area. Each week the class will read an article, either a review or a primary scientific paper, and discuss it. Discussion will be lead by a member of the class. The goal of discussions are twofold: 1) to ensure understanding of hypotheses and how they were evaluated by asking questions and attempting answers, and 2) to learn how an existing study can lead to new hypotheses or ideas that need testing.

 

Grading.- Discussion is the focus of this course. Hence grades will be based on three components.

1.      How well you lead the discussion (100 pts). The discussion leader should give a summary of the paper and the ideas it addresses, and then solicit questions/discussion from the class. Good discussion leaders also mediate and guide the discussion.

2.      Attendance (100 pts). Given the goals of the class, attending and being prepared is critical. I will allow two excused absences without penalty, but additional absences will have an effect on the grade. If students are having difficulty attending, please talk to the instructor as alternative assignments may be possible.

3.      Participation (100 pts). To ensure that all students are prepared to participate, each week everyone will turn in a 1 paragraph summary of the reading and 4 questions they had about the material. Students who actually ask these questions in class or offer answers to other students’ questions will score extra points.